Effect of UV and EMS mutagenesis on xylanase production of Streptomyces thermocarboxydus ME 742 for oil palm waste composting

Pensri Kleangjit, Wasana Suyotha, Wiriya Duangsuwan, Pongsak Noparat

Abstract


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Composting is one of most favored alternative to manage the large quantity of wastes generated from palm oil mill including empty fruit bunches (EFB) and decanter cake (DC) to avoid environmental pollutions. Microorganism is one of factor determinant for the degradation rate of raw material, therefore applying superior microorganism in process is a promising approach to enhance composting efficiency.?? In this study, the main aim was to improve xylanase production by Streptomyces thermocarboxydus ME742, which had been classified as thermotolerant lignocellulolytic bacteria and can be used in compost preparation. Firstly, UV exposure was applied to increase the production of lignocellulolytic enzyme, mainly xylanase. Unfortunately, this method could not induce a significant increase in xylanase production when mixed substrate of EFB and DC was used as nutrient for microbial growth, even they showed clear zone on xylan-containing agar about 10-13 cm bigger than that of wild-type.?? Mutants with enhanced 0.05-0.23 fold in xylanase production were obtained by EMS treatment for 60 min at concentration of 15 ??g/mL. Through cultivation for 5 generations, 8 mutants possessed significantly increase in their xylanase production reached to 1.95-2.06 fold higher than wild type. Among these mutants, MEEMS16 was most genetically stable mutant which produced xylanase at 704.90 ?? 21.91 U/g substrate, accounted to 2.06 fold of wild type. This study indicates that EMS was an effective mutagenic agent to generate mutation of S. thermocarboxydus ME742 with promising xylanase activity for use in decomposition of EFB and DC.


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References


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